FIRST EVIDENCE OF INTRACLONAL GENETIC EXCHANGE IN TRYPANOSOMATIDS USING TWO LEISHMANIA INFANTUM FLUORESCENT TRANSGENIC CLONES.

First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones.

The mode of reproduction in Leishmania spp has been argued to be essentially clonal.However, recent data (genetic analysis of populations and co-infections in sand flies) have proposed the existence of a non-obligate sexual cycle in the extracellular stage of the parasite within the sand fly vector.In this article we propose the existence ct104277

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Dissociating Retrieval Success from Incidental Encoding Activity during Emotional Memory Retrieval, in the Medial Temporal Lobe

The memory-enhancing effect of emotion, during encoding and retrieval, has been linked to the engagement of emotion- and memory-related medial temporal lobe (MTL) regions (amygdala-AMY; hippocampus-HC; parahippocampus-PHC).However, recognition tasks used to investigate the neural correlates of retrieval trucf make it difficult to distinguish MTL en

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Characterization of Genome-Wide DNA Methylation and Hydroxymethylation in Mouse Arcuate Nucleus of Hypothalamus During Puberty Process

Background: Pulsatile pituitary gonadotropin low profile barn door kit secretion governed by hypothalamic gonadotropin-releasing hormone (GnRH) is essential for the pubertal onset.The epigenetic mechanism underlying the activation of GnRH-dependent regulatory axis in hypothalamus remains elusive.This study aims to explore the potential correlation

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Trichostatin A stabilizes the expression of pluripotent genes in human mesenchymal stem cells during ex vivo expansion.

BACKGROUND: Mesenchymal stem cells (MSCs) have been considered as ideal cells for the treatment of a variety of diseases.However, aging tennessee titans dog bandana and spontaneous differentiation of MSCs during culture expansion dampen their effectiveness.Previous studies suggest that ex vivo aging of MSCs is largely caused by epigenetic changes p

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